DNA Nanocage Backbone Modification Service
As a drug carrier, DNA nanocage has a large loading capacity, low cytotoxicity, and will not cause a serious immune response; at the same time, it has more modified sites and can be modified to achieve targeted drug delivery. The structure of DNA nanocage has strong programmability, and many complex cage structures can be obtained through sequence design. At the same time, it is simple to synthesize, easy to obtain, high self-assembly efficiency, good stability and biocompatibility, and strong in vivo degradation ability, and can enter living cells non-invasively and efficiently. Creative BioMart Nanocage provide you with comprehensive DNA nanocage backbone modification service according to your scientific needs.
DNA Nanocage Backbone Modification Services We Offer
The natural DNA backbone consists of repeated deoxyribose and phosphate groups. It is the target of DNase that catalyzes the hydrolytic cleavage of phosphodiester bonds. The chemical modification of the backbone can significantly improve its biological stability by preventing the attack of nucleases. Creative BioMart Nanocage can provide a variety of backbone-modified nucleic acids containing non-natural ingredients, which can be called synthetic nucleic acid polymers, including but not limited to:

The functions of these hybrid nanostructures are no less than their natural mimic counterparts. After completing the DNA nanocage backbone modification, we also provide corresponding structure and function characterization services.
Provided by Clients
Please inform us of your specific DNA nanocage backbone modification service details, and we can provide customized solutions for different projects.
Deliverables

- Xeno-nucleic acids (XNA) modification results
- Peptide nucleic acids (PNA) modification results
- Locked nucleic acids (LNA) modification results
- Threose nucleic acids (TNA) modification results
- Phosphorothioate DNA modification results
- Characterization of modified DNA nanocage structure
- Functional characterization of modified DNA nanocage
Confidentiality statement
Creative BioMart Nanocage has many business partners and knows the importance of confidentiality to these companies. We attach great importance to confidentiality, sign a confidentiality agreement before communicating with you, and adopt multiple firewalls and safeguards to protect your privacy.
Our Advantages
- The scientific research team of Creative BioMart Nanocage is composed of doctoral-level scientists and business managers with many years of work experience. They have professional technical level and can meet your various scientific research needs.
- Creative BioMart Nanocage cooperates with scientists from many pharmaceutical and biotechnology companies. We have a wealth of knowledge and experience to provide quality assurance services.
Why Choose Us?
Creative BioMart Nanocage provides professional DNA nanocage backbone modification service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop DNA nanocage backbone modification service. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.