DNA Nanocage Loading Chemical Drug Service

Research Progress in DNA Nanocage Drug Delivery

Kim et al. [1] designed an L-DNA tetrahedron (DOX@L-TD) with anti-tumor drug DOX. The DNA tetrahedron is the simplest three-dimensional DNA nanocage with stable structure and simple and fast preparation process. This system can directly penetrate the cell membrane without transfection reagent, greatly enhances the EPR effect and cell uptake, and can continuously release DOX in the tumor. It is reported that scientists used DNA nanocages as the carrier of DOX and combined with nucleic acid aptamers. This preparation realized the targeted delivery of DOX to tumor tissues through the active targeting of nucleic acid aptamers, and significantly reduced the effect of DOX on the heart. Adverse reactions, showing good biocompatibility

Figure 1. Schematic illustration of mirror DNA nanostructures for tumor-specific delivery of anticancer drugs. (Kim KR, Kim HY, Lee YD, et al.2016)

DNA Nanocage Loading Chemical Drug Service We Offer

DNA nanocage contains small molecule chemical drugs, which can prevent drugs from being quickly cleared during the systemic circulation, reduce the amount of drugs used, and at the same time can enhance the uptake effect of cells and improve targeting. Creative BioMart Nanocage provide professional DNA nanocage loading chemical drug service to meet your scientific research needs. You can inform us the small chemical drugs you want to load according to your scientific research needs, and our experts will communicate with you the details of the service.

Our Advantages

• Creative BioMart Nanocage has professional DNA nanocage drug delivery experts. You only need to briefly describe your service needs, and our experts will provide you with customized solutions and communicate the details of the service with you.
• Creative BioMart Nanocage has successfully supported multiple DNA nanocage drug delivery projects. Our team has deep scientific literacy and years of experience in the industry, and can bring more profound and in-depth professional knowledge and rich experience to customers.
• Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: to provide customers with efficient, fast, practical and feasible solutions.

Why Choose Us?

Creative BioMart Nanocage provides you with a complete and optimized DNA nanocage loading chemical drug service. Our drug loading service has been verified in a variety of drug types, with robust and specific performance. Tell us your needs, we can help you design and complete DNA nanocage loading chemical drug service through strict quality control and advanced nanocage platform. Don't hesitate to contact us, we guarantee to provide our customers with the most reliable and efficient research services, shorter turnaround times and lower prices.

Reference

• Kim KR, Kim HY, Lee YD, et al. Self-assembled mirror DNA nanostructures for tumor-specific delivery of anticancer drugs. J Control Release, 2016,243: 121-131.