Ferritin Service
Ferritins are produced in almost all living organisms, such as animals, higher plants, fungi and bacteria. Their function in nature is regulation of iron homeostasis by sorting excess iron in its core. It catalyzes the oxidation of iron from ferrous to ferric forms and can store approximately 4500 iron (Fe3+) irons. This function is used for accumulation of metal ions, including Fe, as well as Pt, Pd, Cu, Ag, Co, Gd, etc., in the central cavity of ferritin. They are composed of 24 subunits with a mass of approximately 450 kDa, including both heavy and light chains. Ferritin subunits selfassemble into spherical, cage-like nanoparticles. To summarize, it has adequate structural features, stability, and ability to absorb a number of minerals and metals as well as versatility for genetic and chemical modifications of both the interiors and exteriors; these features nominate ferritin as an adequate candidate widely used as carriers for drug delivery.
Figure 1. Comparison between canonical ferritin and DNA-binding protein from starved cells (Dps). (Palombarini F, Fabio E D, Boffi A , et al.)
Ferritin Service We Offer
Our researchers usually need to have a full understanding of the details of ferritin services. They can quickly understand the project situation through simple descriptions, and quickly formulate feasible research plans according to the needs of customers, saving a lot of time for project development. We can offer you with the following ferritin services but not limited to:
- Ferritin Modification Service (Including Ferritin Chemical Modification Service and Ferritin Biological Modification Service)
- Ferritin and Engineered Ferritin Cargo Loading Service
- Ferritin Characterization Service
- Ferritin Purification Service
- Ferritin Production Service
Our Advantages
- Creative BioMart Nanocage can efficiently provide you with ferritin-related services. Our ferritin can easily load targeting moieties, therapeutic agents and imaging agents.
- Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: to provide customers with efficient, fast, practical and feasible solutions.
- We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.
Our Advantages
Please inform us of your ferritin service details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and final product will be delivered to you immediately.
Why choose us?
Creative BioMart Nanocage provides professional ferritin services to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop ferritin service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
References
- Palombarini F, Fabio E D, Boffi A , et al. Ferritin Nanocages for Protein Delivery to Tumor Cells. Molecules, 2020, 25(4):825.
- Lee E J, Na K L, Kim I S. Bioengineered protein-based nanocage for drug delivery. Advanced drug delivery reviews, 2016, 106(Pt A).
