DNA Nanocage Loading Gold Nanoparticles Service

Research Progress in DNA Nanocage Loading siRNA

• Zhang et al. [1] hybridized the single strands of DNA immobilized on the surface of gold nanoparticles (AuNPs) with the single strands on the DNA nanocage, and encased AuNPs in the inner cavity of the DNA nanocage with a clear structure to form AuNP@ DNA nanocage.
Figure 1. Illustration of the challenge of assembling discrete nanoparticle architectures with site-selective functionalization of the spherical nanoparticle surface. (Zhao Z, et al.2011)
• Zhao et al. [2] used DNA origami technology to self-assemble a DNA cage containing Au nanoparticles. The cage has an inner cavity of 10 nm × 10 nm × 21 nm, which is an ideal place for nanoparticle encapsulation and can be used for drug delivery. In addition, the surface of the cage can be modified with probes to improve targeting.

DNA Nanocage Loading Gold Nanoparticles Service We Offer

• Based on the easy modification, addressability and excellent biocompatibility of DNA molecules, DNA nanostructures have been widely used in the fields of materials and biology. Creative BioMart Nanocage uses DNA cages as carriers for nano-gold and anti-cancer drugs, which can achieve the synergistic effects of photothermal and chemotherapy.
• Creative BioMart Nanocage uses DNA origami technology to provide DNA nanocage loading gold nanoparticles service. We provide you with a DNA cage containing Au nanoparticles, which is an ideal place for nanoparticle loading and can be used for drug delivery. In addition, Creative BioMart Nanocage can also be modified with probes to improve targeting.

Our Advantages

• One-stop solution from project design, drug loading and purification
• Faster turnover and lower costs
• Report project progress in time
• Focus on nanocage drug-carrying research

Why Choose Us?

Creative BioMart Nanocage is a renowned nanocage service provider and supports most of the nanocage related services. Creative BioMart Nanocage is committed to perfecting all types of nanocage drug delivery services. We are able to design and complete a set of services as solutions for themed projects. Creative BioMart Nanocage is provides a variety of drug loading services to help our customers accelerate the discovery and development of small molecule drugs and improve the overall success rate of the project. For more detailed information on how we can provide innovative support for your projects, please feel free to contact us.

References

• Zhao Z, Jacovetty E L, Liu Y, et al. Encapsulation of Gold Nanoparticles in a DNA Origami Cage. Angewandte Chemie, 2011, 50(9):2041.
• Zhang C, Li X, Tian C, et al. DNA nanocages swallow gold nanoparticles (AuNPs) to form AuNP@DNA cage core-shell structures. Acs Nano, 2014, 8(2):1130-5.