Ferritin Enzyme Modification Service
The surface modification of ferritin can attach certain molecules to its polypeptide chain to give ferritin new functions, but its main biological functional groups such as enzyme active sites or ligand recognition sites remain active. Ferritin is a globular protein formed by self-assembly of 24 subunits. The outer surface can be used to connect ligands with special functions, so that ferritin can confer new biological functions. Creative BioMart Nanocage has well-trained technicians and the most advanced biology modification equipment. We will provide you with high-quality ferritin enzyme modification service according to your scientific needs.
Ferritin enzyme modification service We Offer
Creative BioMart Nanocage focuses on comprehensive services for ferritin enzyme modification service. Creative BioMart Nanocage has well-trained technicians and the most advanced ferritin enzyme modification service technology to meet your scientific research needs. We can provide the following enzyme modification services, including but not limited to:
- Transglutaminases (Tgases) modification service
Creative BioMart Nanocage provides transglutaminase (TGases) modification services. Transglutaminase is an enzyme that can catalyze the transacyl reaction, which leads to covalent cross-linking between proteins (or polypeptides). This type of enzyme can form crosslinks between the glutamate γ amide of the protein and the ε amino group of lysine. TGase is selective for some special glutamic acids, which are related to the flexibility of amino acid sequence, and acyl donors need to have sufficient conformational flexibility. This modification method is often used for selective site modification.
Figure 1. Structure of transglutaminase.
- Microbial transglutaminase (mTGase) modification service
Creative BioMart Nanocage provides microbial transglutaminase (mTGase) modification service, which can be used for the PEG site-specific modification of the glutamine residues of some proteins. mTGase has strict requirements for acyl donors. For example, it only recognizes a few glutamic acids inserted into specific amino sequences.
- Custom Ferritin Enzyme Modification Service
We can provide customized iron protease modification services according to the scientific research needs of customers. You can provide the details of your needs, and our experts will provide you with matching experimental programs and designs.
Our Advantages
- Creative BioMart Nanocage can efficiently generate highly functionalized ferritin, which can easily load targeting moieties, therapeutic agents and imaging agents.
- Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: to provide customers with efficient, fast, practical and feasible solutions.
- We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.
Service Procedure
Please inform us of your ferritin enzyme modification service project details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals.
Why choose us?
Creative BioMart Nanocage provides professional ferritin enzyme modification service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop ferritin enzyme modification service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
Reference
- Greenberg C S, Birckbichler P J, Rice R H . Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. Faseb Journal, 1991, 5(15):3071-3077.
