Gold Nanocages Drug Delivery

Gold nanocages represent attractive and promising applications for drug delivery in special environments with their unique size, superficially tunable functionality, and controllable drug release. Gold nanoparticles have unique properties that aid in molecular diagnosis, therapy, and devices used in a variety of medical procedures. Since they are also biocompatible, gold nanocages hold promise as contrast agents for optical coherence tomography. Gold nanocages also absorb light and heat (photothermal effect), killing surrounding cancer cells. Nanocages have been functionalized with cancer-specific antibodies. Now, Creative BioMart Nanocage provides you with a variety of gold nanocages drug delivery techonology services to meet your scientific research needs.

Figure 1. Gold nanoparticles were synthesized according to the method of Brust and Schiffrin. (Yafout M, et al. 2021)

Gold Nanocages Drug Delivery Technology

• We can provide drug delivery services for gold nanocages, especially targeted delivery services for antitumor drugs and antibiotics. Antineoplastic agents and antibiotics are the most popular targets for targeted delivery. We provide targeted delivery services for the following antineoplastic agents, including but not limited to:

Paclitaxel	Methotrexate	Daunorubici	Cysteine
6-mercaptopurine	Dodecylcysteine	Sulfonamide	5-fluorouracil
Platinum complex	Cahelaride	Tamoxifen	Herceptin

• We provide in vitro and in vivo experiments to determine whether gold nanocage particles can be delivered directly to tumor sites.
• In addition, we also provide the drug controlled release service of gold nanocages. Specifically, we encapsulate drug molecules in gold nanocages and release them through photothermal effect under the control of near-infrared light. The photothermal effect remotely controls the release of drug molecules.

Gold Nanocages Drug Delivery Approaches We Offer

• In passive targeting, we make the vasculature of the tumor pervasively leaky through the enhanced penetration and retention (EPR) effect, thereby predisposing the nanoparticles to accumulation in the tumor.
• In active targeting, we can bind some specific ligands to gold nanocages, such as monoclonal antibodies or peptides. These ligands then interact with receptors (specific biomarkers) on tumor cells, allowing endocytosis and drug delivery.

Figure 2. Functionalization of gold nanocages with different types of ligands. (Yafout M, et al. 2021)

Provided by Clients

Please inform us of your specific gold nanocage drug delivery technology service details, and we can provide customized solutions for different projects.

Confidentiality Statement

We attach great importance to confidentiality, sign a confidentiality agreement before communicating with you, and adopt multiple firewalls and safeguards to protect your privacy.

Why Choose Us?

Creative BioMart Nanocage provides corresponding gold nanocage drug delivery service. We have many years of experience in gold nanocages drug delivery, and our services have proven to be very useful for understanding the different stages of nanocage development (even in different fields such as materials science). The Creative BioMart Nanocage team has worked in this field for more than ten years and published his research results in top scientific journals. If you have any demand for gold nanocages modification service, please feel free to contact us.

References

• Yafout M, Ousaid A, Khayati Y, et al. Gold nanoparticles as a drug delivery system for standard chemotherapeutics: A new lead for targeted pharmacological cancer treatments. Scientific African, 2021, 11(Suppl):e00685.