DNA Nanocage Encapsulation Service

The encapsulation of DNA nanocages by functional reagents can also enhance its stability. For example, Shih et al. [1] encapsulate DNA origami structures by forming liposomes in situ around the structure (Perrault and Shih, 2014). The lipid bilayer envelope not only isolates the DNA nanocarriers from the enzymes in the serum, but also changes their surface characteristics, which is important for determining immune response and biodistribution. After lipid bilayer encapsulation, the immune activation of the DNA structure was reduced by 2 orders of magnitude, and the pharmacokinetic bioavailability was increased by 17 times. Now, Creative BioMart Nanocage provide you with comprehensive DNA nanocage encapsulation service according to your scientific needs.

DNA Nanocage Encapsulation Services We Offer

Creative BioMart Nanocage has established a mature and reliable DNA nanocage packaging service, you can choose the appropriate packaging service according to your needs.

• DNA nanocage cationic polymer encapsulate service

Creative BioMart Nanocage provides DNA nanocage cationic polymer encapsulation services. Cationic polymer is another material used for DNA structural encapsulation. Cationic polymers can be closely adsorbed on the negatively charged phosphate backbone of DNA through electrostatic interactions. We will design a suitable molecular ratio of polymer to DNA structure for you, because an improper ratio may cause unnecessary aggregation or distortion.


• DNA nanocage polyethylene glycol (PEG) encapsulate service

As a widely used anti-conditioning agent, polyethylene glycol (PEG) has been shown to have broad app  lication potential in drug delivery. Introducing PEG into the coating polymer is a common strategy to reduce non-specific protein adsorption. Creative BioMart Nanocage uses PEG to encapsulate the DNA nanocage, which helps the DNA nanocage avoid rapid renal clearance.

Provided by Clients

Please inform us of your specific DNA nanocage encapsulation service details, and we can provide customized solutions for different projects.

Deliverables

1. Related experimental results raw data
2. Data analysis
3. Image and result analysis
4. Experimental report

Confidentiality statement

Creative BioMart Nanocage has many business partners and knows the importance of confidentiality to these companies. We attach great importance to confidentiality, sign a confidentiality agreement before communicating with you, and adopt multiple firewalls and safeguards to protect your privacy.

Our Advantages

• Creative BioMart Nanocage provides you with professional DNA nanocage encapsulation service. You can directly contact our staff to provide your scientific research needs.
• Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service. Provide customers with efficient and feasible solutions.

Why Choose Us?

Creative BioMart Nanocage is a well-known DNA nanocage service provider and supports most nanocage related services. We are able to design and complete a set of services as solutions for themed projects. Creative BioMart Nanocage provides DNA nanocage packaging services to help our customers accelerate the discovery and development of scientific research projects and increase the overall success rate of the projects. For more detailed information on how we can provide innovative support for your projects, please feel free to contact us.

Reference

1. Hahn, J, Wickham, S. F, Shih, W. M and Perrault, S. D. Addressing the instability of DNA nanostructures in tissue culture. ACS Nano.2014, 8, 8765–8775