DNA Nanocage Protein Conjugate
Nanotechnology applied to drug delivery systems can improve the solubility of drugs, change their biodistribution and in vivo kinetic properties, and can also control drug release, avoiding the lack of tissue specificity and potential caused by traditional drug delivery systems. The toxicity and other shortcomings. DNA nanocage is a nano-scale polyhedron with a certain spatial structure that is self-assembled by multiple DNA oligonucleotide chains through the principle of base complementary pairing. DNA nanocage as a protein carrier can protect the protein from the external environment (such as the biodegradation effect of enzymes on the protein) to protect the activity of the protein and improve the stability of the protein. Now, Creative BioMart Nanocage offer you with professional DNA nanocage protein conjugate service according to your scientific needs.
Figure 1. A temperature-controlled DNA cage for capture and release of the enzyme horseradish peroxidase. (Juul, S.; Iacovelli, F.; Falconi, M.; et al.2013)DNA Nanocage Protein Conjugate We Offer
Functional modification of the DNA nanocage can realize the multiple uses of the DNA nanocage. Creative BioMart Nanocage can use a variety of technologies to provide protein conjugate services for DNA nanocages. You can choose the following proteins according to your scientific research needs:
- Bovine serum albumin
- Streptavidin
- Cytochrome c
- Azurin
- Horseradish Peroxidase (HRP)
- Glucose Oxidase (GOX)
Creative BioMart Nanocage can load other biologically active protein on the DNA nanocage, and can also introduce other active structures to give the DNA nanocage more biological functions. It can be lysed under the action of light and released the biologically active ingredients contained in it. Modifications can achieve targeted drug delivery.
Our Advantages
- Creative BioMart Nanocage can achieve targeted drug delivery through DNA nanocage protein modification.
- Creative BioMart Nanocage provides you with a variety of DNA nanocage protein conjugate service for your choice, our DNA nanocage protein conjugate service can easily loaded with targeting moieties, therapeutics, and imaging agents.
- Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: which has been established to provide customers with efficient, fast, practical and feasible solutions.
- We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.
Service Procedure
Please inform us of your DNA nanocage protein conjugate service details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and final product will be delivered to you immediately.
Why choose us?
Creative BioMart Nanocage provides professional DNA nanocage protein conjugate service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop DNA nanocage protein conjugate service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
References
- Arun Richard Chandrasekaran, Oksana Levchenko. Chem. Mater. 2016, 28, 16, 5569–5581.
- Juul, S.; Iacovelli, F.; Falconi, M.; et al. Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage. ACS Nano 2013, 7, 9724-9734.
