Liposomes
Introduction to Liposomes
Liposome is a new nanostructure for the encapsulation and delivery of bioactive agents. It consists of lipid bilayers that are amphiphilic carriers for targeted drug delivery. Liposomes possess particular properties such as excellent biocompatibility and biodegradability, highly efficient drug encapsulation, sustained release, long shelf-life and low toxicity.
Among numerous brilliant new drug and gene delivery systems, liposomes provide an advanced technology to carry active molecules to the specific site of action, and various formulations are in clinical use nowadays. Versatile properties of liposomes are manipulated by modifying liposome formulations to address different drug delivery considerations in treatment of cancer, antibacterial, antifungal, immunomodulation, diagnostics, etc.
Fig1. Structure of a liposome. (Saniha Ajith, 2023)
Service Details
We can provide a series of services from design to production to evaluation, all according to your actual needs to develop the final solution. The specific service content includes but is not limited to the following aspects:
- Functional liposomes production
We can design and synthesize liposomes with specific functions and properties according to the needs of our customers. Design liposomal complexes based on your specific needs, such as drug delivery goals, desired functions, etc.
- Drug loading
The appropriate drug loading method needs to consider factors such as the physicochemical properties of the drug, the required release kinetics, the biocompatibility and stability of the carrier, and your needs. We offer physical loading, electrostatic adsorption, chemical bonding and other methods.
- Phospholipids modification
Some phospholipid modifications can be used to improve drug delivery systems, enhance research on biofilm models, and develop novel diagnostic tools. We supply phatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS) and other modified forms for you to choose.
- Functional measurement
The targeting, controlled release, biocompatibility and therapeutic effect of liposomes will be verified by in vitro and in vivo experiments. The quality and properties of liposomes will be strictly measured and controlled by various analytical techniques, such as particle size analysis, zeta potential measurement, transmission electron microscopy, etc.
Why choose us?
- The expert team of Creative BioMart Nanocage has a multidisciplinary background, including medicine, pharmacy, molecular biology, bioinformatics, etc. We attach great importance to innovation and practice.
- We can provide customized services. Not limited to the types of services mentioned above, products can be designed according to your specific needs.
- Unique technologies for drug industries
- High efficiency and quality
Creative BioMart Nanocage provides liposome-based delivery design services to meet the scientific research needs of customers. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
References
- Chen, J.; et al. Recent advances and clinical translation of liposomal delivery systems in cancer therapy. Eur J Pharm Sci. 2024;193:106688.
- Ajith, S.; et al. Nanoparticle-based materials in anticancer drug delivery: Current and future prospects. Heliyon. 2023;9(11):e21227.
