Tile-based Hierarchical Assembly Service

Tile-based Hierarchical Assembly Service

Conventional drug molecules diffuse throughout the body where they can affect normal cells next to their intended targets, leading to undesired side effects. In fact, only 5% of all new potential therapeutics have favourable pharmacokinetic and bio-pharmaceutical properties.Recent nanotechnological advances have led to the development of smart nanoparticles which are able to selectively target tissues and deliver therapeutics. DNA has been used to build nanostructures with potential biomedical applications. Due to its inherent characteristics of high stability, biocompatibility and versatility, DNA nanocage is a polymer that is very suitable for generating nanoparticles and can be used in various applications, including cell biosensors, drug delivery, cell Intramolecular detection and in vivo imaging. Now, Creative BioMart Nanocage offer you with professional tile-based hierarchical assembly service according to your scientific needs.

Tile-based hierarchical self-assembly of DNA cages.Figure 1. Tile-based hierarchical self-assembly of DNA cages.

Tile-based Hierarchical Assembly Service We Offer

  • Creative BioMart Nanocage creates tetrahedrons, dodecahedrons or buckyballs by controlling the flexibility and density of the component tiles. Each arm of these star DNA motifs is a four-arm connection, which can self-assemble into a symmetrical DNA polyhedron through sticky-end hybridization.
  • Creative BioMart Nanocage constructs polyhedral DNA nanocages for you. They can also be reconfigured to open and close to encapsulate and release various objects.
  • Creative BioMart Nanocage can extend this strategy to create more complex polyhedra by using DNA motifs with more arms.

Our Advantages

Our Advantages
  • Creative BioMart Nanocage has advanced equipment and experienced scientific research team. Our advanced DNA nanocage platform can provide highly reliable and reproducible results.
  • Creative BioMart Nanocage can generally complete the scoring service within a week. We will send the labeled and purified samples to customers, and we can provide them according to customer requirements.
  • We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.

Service Procedure

Service Procedure

Please inform us of your tile-based hierarchical assembly service details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and final product will be delivered to you immediately.

Why choose us?

Creative BioMart Nanocage provides professional tile-based hierarchical assembly service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop tile-based hierarchical assembly service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

References

  • Arun Richard Chandrasekaran, Oksana Levchenko. Chem. Mater. 2016, 28, 16, 5569–5581.
  • Ottaviani, Alessio, Desideri, et al. Entry, fate and degradation of DNA nanocages in mammalian cells: a matter of receptors.
  • Schoonen L, Hest J V . Functionalization of protein-based nanocages for drug delivery applications. Nanoscale, 2014, 6(13):7124-7141.

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