Exterior Modification of Protein Nanocages
The exterior surface of protein nanocages is engineered to impart increased circulatory half-life, local accumulation, cellular penetration and triggering of specific cellular responses. The unique geometry of protein nanocages allows for multiple ligands and functional molecules to be displayed on their surfaces. Now, Creative BioMart Nanocage can offer you with professional professional exterior modification service of protein nanocages, if you have any needs in this regard, please feel free to contact us.
Figure 1. Exterior modification of protein nanocages. (Uchida, M.et al.2010) Exterior Modification of Protein Nanocages We Offer
Creative BioMart Nanocage focuses on comprehensive services for exterior modification service of protein nanocages. Creative BioMart Nanocage has well-trained technicians and the most advanced nanocage modification technology to meet your scientific research needs. Modifying molecules we can offer include but not limited to:
- Small molecules (e.g. folate)
- Peptides (e.g. RGD, transactivator of transcription 47–57 peptide (cell penetrating peptide)
- Immunoglobulin G binding peptide
- Antibodies (e.g. anti-epidermal growth factor receptor and anti-CD4)
- Nucleotides (e.g. DNA, RNA, aptamers)
- Polymers (e.g. PEG, PGA, poly(lactic-co-glycolic acid), polymethacrylate, polyamidoamine)
Our Advantages
- Creative BioMart Nanocage can extend the half-life of nanocages (such as PEG) and enhance the penetration of cells (such as cell penetrating peptides) by connecting functional ligands. PEG acts as an invisible layer to shield the surface of the nanocage structure. Immunogenic epitope. PEG modification is also conducive to the tunable solubility and structural integrity of protein nanocages.
- Creative BioMart Nanocage can efficiently generate highly functionalized protein nanocages, which can be easily loaded with targeting moieties, therapeutic agents and/or imaging agents.
- Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: which has been established to provide customers with efficient, fast, practical and feasible solutions.
- We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.
Service Procedure
Please inform us of your exterior modification of protein nanocages project details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project.
Why choose us?
Creative BioMart Nanocage provides professional exterior modification of protein nanocages service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop Exterior Modification of Protein Nanocages, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
Reference
- Bhaskar S , Lim S . Engineering protein nanocages as carriers for biomedical applications. Npg Asia Materials, 2017, 9(4):e371.
