Ferritin Sulfhydryl Modification

Ferritin Sulfhydryl Modification

Chemical modification can overcome its own shortcomings or give it new functions by attaching different modifiers to the surface of ferritin, including antibodies, fluorescence, enzymes, polymers, etc. Using antibodies to recognize specific antigens can mediate specific interactions between cells, and the ferritin attached to the antibody has a certain targeting effect. Creative BioMart Nanocage has well-trained technicians and the most advanced ferritin sulfhydryl modification equipment. We will provide you with high-quality protein nanocage modification services. Creative BioMart Nanocage focuses on comprehensive services for ferritin sulfhydryl modification service.

Ferritin sulfhydryl modification service We Offer

The sulfhydryl reaction is a common chemical modification reaction of ferritin. You can choose the reagents according to your needs:

Schematic illustration of thehree interfaces of a process thatt can be exploited to ipart designed functionalities.
  • Halogenated acetyl
  • Alkyl halide
  • Phenyl halide
  • Maleimide

These reactions are affected by the degree of ionization of the reactants and the pH of the reaction solution. Creative BioMart Nanocage selects the most reactive iodoacetic acid to react with the sulfhydryl group of cysteine. We precisely control the pH value (slightly alkaline) and the pH value of iodoacetic acid. The amount (relatively less than the number of sulfhydryl groups in the reaction) can provide a more specific product.

Our Advantages

  • Creative BioMart Nanocage provides professional ferritin chemical modification services. You can choose different modification types according to your scientific research needs.
  • The ferritin chemical modification services provided by Creative BioMart Nanocage can be applied to biological immunoassays, protein labeling, dark-field optical imaging, fluorescence enhancement, surface-enhanced Raman substrates, drug carriers, etc.
  • Creative BioMart Nanocage can efficiently produce highly functionalized ferritin, and can easily load targeting moieties, therapeutic agents and/or imaging agents.
  • Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: to provide customers with efficient, fast and practical solutions.
  • We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.

Service Procedure

Glutamic and aspartic accid: amide formation through activation whith a carbodiimide.

Please inform us of your ferritin sulfhydryl modification service project details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals.

Why choose us?

Creative BioMart Nanocage provides professional ferritin sulfhydryl modification service to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop ferritin sulfhydryl modification service service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

Reference

  • Uchi Da M, Kang S, Reichhardt C, et al. The Ferritin Superfamily: Supramolecular Templates for Materials Synthesis. Biochimica et Biophysica Acta, 2010, 1800(8):834-845.

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