Protein Nanocage Modification
Nanocages (NCs) have become a new class of drug carriers with wide possibilities in multimodal medical treatment and therapeutic diagnostics. Due to its unique characteristics, nanocages can overcome the limitations of anti-cancer chemotherapy or high toxicity caused by the nanocarrier itself. Creative BioMart Nanocage focuses on the comprehensive research of protein nanocage modification service. Creative BioMart Nanocage has well-trained technicians and the most advanced chemical modification equipment. We will provide you with high-quality protein nanocage modification services.
Figure 1. Illustration of the common mode of targeted drug delivery using protein nanocages. (A) Interaction between protein nanocages and their cognate receptors. (B) Interactions between ligands anchored on the protein nanocage surface and their specific receptors. (C) Interactions between antibodies immobilized on the protein nanocage and their cognate antigens. (Ghisaidoobe A B , Chung S J.2015) Introductions
Traditional drug delivery strategies involve drugs which are not targeted towards the desired tissue. This can lead to undesired side effects, as normal cells are affected by the drugs as well. Therefore, new systems are now being developed which combine targeting functionalities with encapsulation of drug cargo. Protein nanocages are highly promising drug delivery platforms due to their perfectly defined structures, biocompatibility, biodegradability and low toxicity. Now, Creative BioMart Nanocage can provide you with professional protein nanocage modification services to meet your scientific research needs.
Protein Nanocage Modification We Offer
Our modification range includes not only protein nanocages, but also different types of NC structures, such as virus-like particle (VLP) DNA NC, supramolecular nanosystems, mixed metal organic NC, gold NC, carbon-based NC and silica NC. Our scope of services includes but is not limited to:
- PEGlyation
- Customized conjugation
- Protein labelling
- Smart polymers modification
- NIPAAm modicifation
- PDDA modification
- Virus-like particles (VLPs) chemical modification
- Antibody modified protein nanocage service
Our Advantages
- Creative BioMart Nanocage provides you with a variety of protein nanocage modification services for your choice, our modified protein nanocages can easily loaded with targeting moieties, therapeutics, and imaging agents.
- Creative BioMart Nanocage will complete your project on time and efficiently. We have professional after-sales service: which has been established to provide customers with efficient, fast, practical and feasible solutions.
- We have established a professional after-sales service team to provide customers with efficient, fast and practical solutions.
Service Procedure
Please inform us of your protein nanocage modification project details through online consultation. We will reply to you in time and provide you with a comprehensive evaluation report on your project, including the feasibility of the project and the detailed experimental plan designed by our professionals. As our condition optimization is completed, the result report and final product will be delivered to you immediately.
Why choose us?
Creative BioMart Nanocage provides professional protein nanocage modification services to meet the scientific research needs of customers. Creative BioMart Nanocage relies on world-class technical expertise, we provide customers with the best quality one-stop protein nanocage modification service, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
References
- Ghisaidoobe A B , Chung S J. Functionalized protein nanocages as a platform of targeted therapy and immunodetection. Nanomedicine, 2015, 10(24):3579-3595.
- Schoonen L, Hest J V. Functionalization of protein-based nanocages for drug delivery applications. Nanoscale, 2014, 6(13):7124-7141.
